9EF9

Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with three DILP5, asymmetric conformation

Summary for 9EF9

• Entry DOI: 10.2210/pdb9ef9/pdb
• EMDB information: 47971
• Descriptor: Insulin-like receptor, DILP5 A-chain, DILP5 B-chain, ... (4 entities in total)
• Functional Keywords: insulin receptor, dilp, structural protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 8
• Total formula weight: 501800.21

Authors

Bai, X.C. (deposition date: 2024-11-19, release date: 2025-10-01)

• Primary citation: Bai, X.C.; Structural basis of the activation of the Drosophila insulin receptor by three Drosophila insulin-like peptides; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.6 Å)