9EF5

Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with one DILP2, asymmetric conformation

Summary for 9EF5

• Entry DOI: 10.2210/pdb9ef5/pdb
• EMDB information: 47970
• Descriptor: Insulin-like receptor, DILP2 B-chain, DILP2 A-chain, ... (4 entities in total)
• Functional Keywords: insulin receptor, dilp, structural protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 4
• Total formula weight: 489471.27

Authors

Bai, X.C. (deposition date: 2024-11-19, release date: 2025-10-01)

• Primary citation: Bai, X.C.; Structural basis of the activation of the Drosophila insulin receptor by three Drosophila insulin-like peptides; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.7 Å)