9E4Y
GluA2-gamma2 complex bound to memantine, glutamate, and cyclothiazide
Summary for 9E4Y
Entry DOI | 10.2210/pdb9e4y/pdb |
EMDB information | 47520 |
Descriptor | Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit, Memantine, ... (5 entities in total) |
Functional Keywords | ligand-gated ion channel, ionotropic glutamate receptor, ampa receptor, ion channel, transport protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 8 |
Total formula weight | 458232.02 |
Authors | Montano Romero, A.,Carrillo, E.,Jayaraman, V.,Twomey, E.C. (deposition date: 2024-10-25, release date: 2025-06-25) |
Primary citation | Carrillo, E.,Montano Romero, A.,Gonzalez, C.U.,Turcu, A.L.,Chen, S.,Chen, H.,Pan, H.,Vazquez, S.,Twomey, E.C.,Jayarman, V. Memantine Inhibits Calcium-Permeable AMPA Receptors To Be Published, |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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