9DXP

Cryo-EM structure of human OATP1C1 in complex with thyroid hormone T4

Summary for 9DXP

• Entry DOI: 10.2210/pdb9dxp/pdb
• EMDB information: 47294
• Descriptor: Solute carrier organic anion transporter family member 1C1, 3,5,3',5'-TETRAIODO-L-THYRONINE, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total)
• Functional Keywords: slc transporter, thyroid hormone, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 83802.92

Authors

Ge, Y.,Dou, T.,Jiang, J.,Huang, P. (deposition date: 2024-10-11, release date: 2025-07-16)

• Primary citation: Ge, Y.,Dou, T.,Nguyen, T.U.,Yadav, G.P.,Wensel, T.G.,Jiang, J.,Huang, P.; Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.3 Å)