9DW3

Human mitochondrial ClpP in complex with Bortezomib

Summary for 9DW3

• Entry DOI: 10.2210/pdb9dw3/pdb
• EMDB information: 47234
• Descriptor: ATP-dependent Clp protease proteolytic subunit, mitochondrial, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE (2 entities in total)
• Functional Keywords: mitochondrial protein, serine protease, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 14
• Total formula weight: 342678.48

Authors

Chen, W. (deposition date: 2024-10-08, release date: 2025-10-15)

• Primary citation: Chen, W.C.; Assembly and proteolytic activation human ClpXP defined by cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)