9DIR

Cryo-EM structure of the heme/hemoglobin transporter ChuA, in complex with de novo designed binder G7

This is a non-PDB format compatible entry.

Summary for 9DIR

• Entry DOI: 10.2210/pdb9dir/pdb
• Related: 9DHE
• EMDB information: 46916
• Descriptor: ChuA binding protein G7, Outer membrane heme/hemoglobin receptor (2 entities in total)
• Functional Keywords: tonb-dependent transporter, chua, heme, hemoglobin, outer-membrane, de novo designed protein, binding protein, transport protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 85020.07

Authors

Fox, D.,Venugopal, H.,Lupton, C.J.,Spicer, B.A.,Grinter, R. (deposition date: 2024-09-05, release date: 2025-05-21)

• Primary citation: Fox, D.R.,Asadollahi, K.,Samuels, I.,Spicer, B.A.,Kropp, A.,Lupton, C.J.,Lim, K.,Wang, C.,Venugopal, H.,Dramicanin, M.,Knott, G.J.,Grinter, R.; Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins; Nat Commun, 2025

Experimental method

ELECTRON MICROSCOPY (2.97 Å)