9DD7

Cryo-EM structure of neutralizing human antibody D48 in complex with HSV-1 glycoprotein B trimer gB-Ecto.516P.531E.DS

Summary for 9DD7

• Entry DOI: 10.2210/pdb9dd7/pdb
• EMDB information: 46759
• Descriptor: Glycoprotein B, D48 heavy chain, D48 light chain, ... (6 entities in total)
• Functional Keywords: immune complex, neutralization, herpes fusogen, viral protein
• Biological source: Human alphaherpesvirus 1 (Herpes simplex virus type 1); More
• Total number of polymer chains: 9
• Total formula weight: 350747.68

Authors

Roark, R.S.,Shapiro, L.,Kwong, P.D. (deposition date: 2024-08-27, release date: 2025-09-10)

• Primary citation: Roark, R.S.,Shapiro, L.,Kwong, P.D.; Prefusion structure and neutralization of HSV-1 glycoprotein B; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.1 Å)