9D9N

Crystal structure of NDM-1 complexed with compound 5

This is a non-PDB format compatible entry.

Summary for 9D9N

• Entry DOI: 10.2210/pdb9d9n/pdb
• Related: 9D2U 9D54 9D5Q 9D5R 9D8T
• Descriptor: Metallo-beta-lactamase type 2, {[1-methyl-2-oxo-7-(pyrrolidin-1-yl)-1,2-dihydroquinolin-4-yl]methyl}phosphonic acid, GLYCEROL, ... (5 entities in total)
• Functional Keywords: inhibitor, beta-lactamase, complex, ndm, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 50940.37

Authors

Jacobs, L.M.C.,Chen, Y. (deposition date: 2024-08-21, release date: 2025-09-03)

• Primary citation: Jacobs, L.M.C.,Chen, Y.,Renslo, A.; Hit to Lead Optimization of Heteroaryl Phosphonates Reversible, Broad-Spectrum Inhibitors of Serine and Metallo Carbapenemases.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)