9D5R

Crystal structure of KPC-2 complexed with compound 22

This is a non-PDB format compatible entry.

Summary for 9D5R

• Entry DOI: 10.2210/pdb9d5r/pdb
• Related: 9D2U 9D54 9D5Q
• Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, {[7-bromo-1-(cyclopentylmethyl)-3-methyl-2-oxo-1,2-dihydroquinolin-4-yl]methyl}phosphonic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, beta-lactamase, complex, kpc, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 31693.24

Authors

Jacobs, L.M.C.,Chen, Y. (deposition date: 2024-08-14, release date: 2025-08-20)

• Primary citation: Jacobs, L.M.C.,Chen, Y.,Renslo, A.; Hit to Lead Optimization of Heteroaryl Phosphonates Reversible, Broad-Spectrum Inhibitors of Serine and Metallo Carbapenemases.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)