9CY5

Dyrk1a bound to a competitive inhibitor

This is a non-PDB format compatible entry.

Summary for 9CY5

• Entry DOI: 10.2210/pdb9cy5/pdb
• Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, (4P)-4-{(4M)-4-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]quinazolin-6-yl}pyridin-2-amine, TETRAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: kinase, inhibitor, complex, alzheimer's disease, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 85900.75

Authors

Montfort, W.R. (deposition date: 2024-08-01, release date: 2025-10-22)

• Primary citation: Montfort, W.R.; Dyrk1a bound to a competitive inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.49 Å)