9CKV

Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin

Summary for 9CKV

• Entry DOI: 10.2210/pdb9ckv/pdb
• EMDB information: 45655
• Descriptor: Integrin alpha-5, Integrin beta-1, NeoNectin, ... (9 entities in total)
• Functional Keywords: a5b1, de novo, tissue regeneration, extracellular matrix protein, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 206835.25

Authors

Werther, R.,Nguyen, A.,Estrada Alamo, K.A.,Wang, X.,Campbell, M.G. (deposition date: 2024-07-09, release date: 2024-07-17)

• Primary citation: Wang, X.,Guillem-Marti, J.,Kumar, S.,Lee, D.S.,Cabrerizo-Aguado, D.,Werther, R.,Estrada Alamo, K.A.,Zhao, Y.T.,Nguyen, A.,Kopyeva, I.,Huang, B.,Li, J.,Hao, Y.,Li, X.,Brizuela-Velasco, A.,Murray, A.N.,Gerben, S.,Roy, A.,DeForest, C.A.,Springer, T.,Ruohola-Baker, H.,Cooper, J.A.,Campbell, M.G.,Maria Manero, J.,Ginebra, M.,Baker, D.; De Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.19 Å)