9CKV
Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin
Summary for 9CKV
Entry DOI | 10.2210/pdb9ckv/pdb |
EMDB information | 45655 |
Descriptor | Integrin alpha-5, Integrin beta-1, NeoNectin, ... (9 entities in total) |
Functional Keywords | a5b1, de novo, tissue regeneration, extracellular matrix protein, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 206835.25 |
Authors | Werther, R.,Nguyen, A.,Estrada Alamo, K.A.,Wang, X.,Campbell, M.G. (deposition date: 2024-07-09, release date: 2024-07-17) |
Primary citation | Wang, X.,Guillem-Marti, J.,Kumar, S.,Lee, D.S.,Cabrerizo-Aguado, D.,Werther, R.,Estrada Alamo, K.A.,Zhao, Y.T.,Nguyen, A.,Kopyeva, I.,Huang, B.,Li, J.,Hao, Y.,Li, X.,Brizuela-Velasco, A.,Murray, A.N.,Gerben, S.,Roy, A.,DeForest, C.A.,Springer, T.,Ruohola-Baker, H.,Cooper, J.A.,Campbell, M.G.,Maria Manero, J.,Ginebra, M.,Baker, D. De Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.19 Å) |
Structure validation
Download full validation report