9CKT

X-ray diffraction structure of papain co-crystallized with E-64

Summary for 9CKT

Entry DOI	10.2210/pdb9ckt/pdb
Related	9CKW 9CKY 9CLH 9EG7
Descriptor	Papain, METHANOL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, ... (4 entities in total)
Functional Keywords	protease, complex, inhibitor-bound, hydrolase
Biological source	Carica papaya (papaya)
Total number of polymer chains	1
Total formula weight	23844.77
Authors	Vlahakis, N.W.,Rodriguez, J.A. (deposition date: 2024-07-09, release date: 2025-06-04)
Primary citation	Liu, M.,Zang, X.,Vlahakis, N.W.,Rodriguez, J.A.,Ohashi, M.,Tang, Y. Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors Nat.Chem.Biol., 2025 Cited by DOI: 10.1038/s41589-025-01907-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation