9CK0
Cocrystal of PPARg LBD and NFKBIB / IKBB peptide with agonist GW1929
Summary for 9CK0
Entry DOI | 10.2210/pdb9ck0/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, NF-kappa-B inhibitor beta, (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid (3 entities in total) |
Functional Keywords | nuclear receptor, pparg, ppar gamma, alpha helix, nfkb, nfkb inhibitor, inflammation, type ii diabetes, dna binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 34428.08 |
Authors | Nemetchek, M.D.,McClelland, L.J.,Hughes, T.S. (deposition date: 2024-07-08, release date: 2024-07-17) |
Primary citation | Nemetchek, M.D.,Hughes, T.S. Cocrystal of PPARg LBD with NFKBIB / IKBB peptide containing N-anchor motif LxxLL and agonist GW1929 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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