9CIW
Penguinpox cGAMP PDE H72A mutant in complex with 2'3'-cGAMP
This is a non-PDB format compatible entry.
Summary for 9CIW
Entry DOI | 10.2210/pdb9ciw/pdb |
Descriptor | Penguinpox cGAMP PDE, [(2~{R},3~{R},4~{R},5~{S})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl [(2~{R},3~{R},4~{S},5~{R})-2-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-5-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl] hydrogen phosphate (3 entities in total) |
Functional Keywords | immune evasion, phosphodiesterase, viral protein |
Biological source | Penguinpox virus |
Total number of polymer chains | 4 |
Total formula weight | 92689.73 |
Authors | Hobbs, S.J.,Nomburg, J.,Doudna, J.A.,Kranzusch, P.J. (deposition date: 2024-07-05, release date: 2024-09-04) |
Primary citation | Hobbs, S.J.,Nomburg, J.,Doudna, J.A.,Kranzusch, P.J. Animal and bacterial viruses share conserved mechanisms of immune evasion Cell(Cambridge,Mass.), 2024 Cited by DOI: 10.1016/j.cell.2024.07.057PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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