9CIW

Penguinpox cGAMP PDE H72A mutant in complex with 2'3'-cGAMP

This is a non-PDB format compatible entry.

Summary for 9CIW

• Entry DOI: 10.2210/pdb9ciw/pdb
• Descriptor: Penguinpox cGAMP PDE, [(2~{R},3~{R},4~{R},5~{S})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl [(2~{R},3~{R},4~{S},5~{R})-2-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-5-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl] hydrogen phosphate (3 entities in total)
• Functional Keywords: immune evasion, phosphodiesterase, viral protein
• Biological source: Penguinpox virus
• Total number of polymer chains: 4
• Total formula weight: 92689.73

Authors

Hobbs, S.J.,Nomburg, J.,Doudna, J.A.,Kranzusch, P.J. (deposition date: 2024-07-05, release date: 2024-09-04)

• Primary citation: Hobbs, S.J.,Nomburg, J.,Doudna, J.A.,Kranzusch, P.J.; Animal and bacterial viruses share conserved mechanisms of immune evasion; Cell(Cambridge,Mass.), 2024; DOI: 10.1016/j.cell.2024.07.057

Experimental method

X-RAY DIFFRACTION (2.4 Å)