9CCR

Crystal structure of the EspE7 thioesterase mutant R35A from the esperamicin biosynthetic pathway at 1.6 A

Summary for 9CCR

• Entry DOI: 10.2210/pdb9ccr/pdb
• Related: 5vpj
• Descriptor: Thioesterase, POTASSIUM ION, DODECYL-COA, ... (4 entities in total)
• Functional Keywords: thioesterase, hot-dog, enediyne biosynthetic pathway, esperamicin biosynthesis, natural product biosynthesis, hydrolase
• Biological source: Actinomadura verrucosospora
• Total number of polymer chains: 4
• Total formula weight: 84886.96

Authors

Miller, M.D.,Hankore, E.D.,Xu, W.,Kosgei, A.J.,Bhardwaj, M.,Thorson, J.S.,Van Lanen, S.G.,Phillips Jr., G.N. (deposition date: 2024-06-23, release date: 2025-06-25)

• Primary citation: Hankore, E.D.,Miller, M.D.,Kosgei, A.J.,Xu, W.,Tan, K.,Endres, M.,Bhardwaj, M.,Joachimiak, G.,Joachimiak, A.,Phillips Jr., G.N.,Thorson, J.S.,Van Lanen, S.G.; Functional and structural studies on the esperamicin thioesterase and progress toward understanding enediyne core biosynthesis; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)