9C9Q

Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain

Summary for 9C9Q

• Entry DOI: 10.2210/pdb9c9q/pdb
• Descriptor: non-specific serine/threonine protein kinase (2 entities in total)
• Functional Keywords: gcn2 integrative stress response, transferase
• Biological source: Thermochaetoides thermophila
• Total number of polymer chains: 2
• Total formula weight: 108465.77

Authors

Bou-Nader, C.,Bahmanjah, S.,Zhang, J. (deposition date: 2024-06-14, release date: 2024-08-21)

• Primary citation: Bou-Nader, C.,Gaikwad, S.,Bahmanjah, S.,Zhang, F.,Hinnebusch, A.G.,Zhang, J.; Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response; Proc.Natl.Acad.Sci.USA, 2024; DOI: 10.1073/pnas.2409628121

Experimental method