9C56
Crystal structure of human PTPN2 in complex with allosteric inhibitor
Summary for 9C56
| Entry DOI | 10.2210/pdb9c56/pdb |
| Related | 9C54 9C55 |
| Descriptor | Tyrosine-protein phosphatase non-receptor type 2, 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE (3 entities in total) |
| Functional Keywords | phosphatase, apo, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 37457.07 |
| Authors | Bester, S.M.,Linwood, R.,Wu, W.-I.,Mou, T.-C. (deposition date: 2024-06-05, release date: 2024-09-04) |
| Primary citation | Bester, S.M.,Linwood, R.,Kataoka, R.,Wu, W.I.,Mou, T.C. Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites. Acta Crystallogr.,Sect.F, 2024 Cited by PubMed: 39177701DOI: 10.1107/S2053230X24007866 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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