9BRM

Crystal Structure of Human G Protein-Coupled Receptor Kinase 5 in Complex with GRL077-22

これはPDB形式変換不可エントリーです。

9BRM の概要

• エントリーDOI: 10.2210/pdb9brm/pdb
• 分子名称: G protein-coupled receptor kinase 5, (3Z)-3-[(4-{[(2S)-2-hydroxy-2-(oxan-4-yl)ethyl]carbamoyl}-3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2-oxo-N-[(1R)-1-phenylethyl]-3,7-dihydro-2H-indole-5-carboxamide (3 entities in total)
• 機能のキーワード: g protein-coupled receptor, gpcr g protein-coupled receptor kinase, grk kinase, signaling protein-inhibitor complex, signaling protein/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 69488.38

構造登録者

Chen, Y.,Tesmer, J.J.G. (登録日: 2024-05-11, 公開日: 2025-11-12)

• 主引用文献: Chen, Y.,Tesmer, J.J.G.; Structures of GRK5 bound to novel inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (2.73 Å)