9BPE
Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase (TthSHMT) in internal aldimine state and folinic acid bound
9BPE の概要
エントリーDOI | 10.2210/pdb9bpe/pdb |
分子名称 | Serine hydroxymethyltransferase, SULFATE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... (5 entities in total) |
機能のキーワード | pyridoxal 5'-phosphate, plp, fold type 1, one carbon metabolism, transferase |
由来する生物種 | Thermus thermophilus HB8 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 89381.91 |
構造登録者 | |
主引用文献 | Drago, V.N.,Phillips, R.S.,Kovalevsky, A. Universality of critical active site glutamate as an acid-base catalyst in serine hydroxymethyltransferase function. Chem Sci, 15:12827-12844, 2024 Cited by PubMed: 39148791DOI: 10.1039/d4sc03187c 主引用文献が同じPDBエントリー |
実験手法 | NEUTRON DIFFRACTION (2.3 Å) X-RAY DIFFRACTION (2 Å) |
構造検証レポート
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