9BJA

C. difficile Tcdb cysteine protease domain in complex with IP6

Summary for 9BJA

• Entry DOI: 10.2210/pdb9bja/pdb
• Descriptor: Toxin B, INOSITOL HEXAKISPHOSPHATE (3 entities in total)
• Functional Keywords: catalytic activity peptidase activity catalytic activity, acting on a protein toxin activity small molecule binding, toxin
• Biological source: Clostridioides difficile
• Total number of polymer chains: 2
• Total formula weight: 61049.03

Authors

Veyron, S.,Cummer, R. (deposition date: 2024-04-25, release date: 2024-07-03)

• Primary citation: Cummer, R.,Grosjean, F.,Bolteau, R.,Vasegh, S.E.,Veyron, S.,Keogh, L.,Trempe, J.-F.,Castagner, B.; Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile Toxin B; Chemrxiv, 2024; DOI: 10.26434/chemrxiv-2024-2cf6g-v2

Experimental method

X-RAY DIFFRACTION (2.1 Å)