9BJA

C. difficile Tcdb cysteine protease domain in complex with IP6

9BJA の概要

• エントリーDOI: 10.2210/pdb9bja/pdb
• 分子名称: Toxin B, INOSITOL HEXAKISPHOSPHATE (3 entities in total)
• 機能のキーワード: catalytic activity peptidase activity catalytic activity, acting on a protein toxin activity small molecule binding, toxin
• 由来する生物種: Clostridioides difficile
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61049.03

構造登録者

Veyron, S.,Cummer, R. (登録日: 2024-04-25, 公開日: 2024-07-03)

• 主引用文献: Cummer, R.,Grosjean, F.,Bolteau, R.,Vasegh, S.E.,Veyron, S.,Keogh, L.,Trempe, J.-F.,Castagner, B.; Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile Toxin B; Chemrxiv, 2024; DOI: 10.26434/chemrxiv-2024-2cf6g-v2

実験手法

X-RAY DIFFRACTION (2.1 Å)