9BIS

Cryo-EM structure of the mammalian peptide transporter PepT2 bound to amoxicillin

9BIS の概要

• エントリーDOI: 10.2210/pdb9bis/pdb
• EMDBエントリー: 44600
• 分子名称: Solute carrier family 15 member 2, nanobody, 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total)
• 機能のキーワード: protein-coupled peptide transporter, peptide transport, antibiotics, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 97339.37

構造登録者

Parker, J.L.,Deme, J.C.,Lea, S.M.,Newstead, S. (登録日: 2024-04-24, 公開日: 2024-07-24)

• 主引用文献: Parker, J.L.,Deme, J.C.,Lichtinger, S.M.,Kuteyi, G.,Biggin, P.C.,Lea, S.M.,Newstead, S.; Structural basis for antibiotic transport and inhibition in the mammalian proton-coupled peptide transporter, PepT2; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.2 Å)