9BG1

Tri-complex of Compound-3, KRAS G12V, and CypA

This is a non-PDB format compatible entry.

Summary for 9BG1

• Entry DOI: 10.2210/pdb9bg1/pdb
• Descriptor: GTPase KRas, Peptidyl-prolyl cis-trans isomerase A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
• Functional Keywords: inhibitor, complex, small gtpase, cancer, tricomplex, signaling protein-inhibitor complex, signaling protein, signaling protein/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 77713.99

Authors

Tomlinson, A.C.A.,Saldajeno-Concar, M.,Knox, J.E.,Yano, J.K. (deposition date: 2024-04-18, release date: 2024-06-12, Last modification date: 2024-06-26)

• Primary citation: Jiang, J.,Jiang, L.,Maldonato, B.J.,Wang, Y.,Holderfield, M.,Aronchik, I.,Winters, I.P.,Salman, Z.,Blaj, C.,Menard, M.,Brodbeck, J.,Chen, Z.,Wei, X.,Rosen, M.J.,Gindin, Y.,Lee, B.J.,Evans, J.W.,Chang, S.,Wang, Z.,Seamon, K.J.,Parsons, D.,Cregg, J.,Marquez, A.,Tomlinson, A.C.A.,Yano, J.K.,Knox, J.E.,Quintana, E.,Aguirre, A.J.,Arbour, K.C.,Reed, A.,Gustafson, W.C.,Gill, A.L.,Koltun, E.S.,Wildes, D.,Smith, J.A.M.,Wang, Z.,Singh, M.; Tri-complex of Compound-3, KRAS G12V, and CypA; To be published,

Experimental method

X-RAY DIFFRACTION (1.51 Å)