9BER

Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab

Summary for 9BER

Entry DOI	10.2210/pdb9ber/pdb
EMDB information	44482 44484 44491
Descriptor	Envelope glycoprotein gp120, Envelope glycoprotein gp41, PGT122 heavy chain, ... (9 entities in total)
Functional Keywords	cd4, hiv-1, sosip, vaccine, gp120, gp41, viral protein-immune system complex, viral protein/immune system
Biological source	Human immunodeficiency virus 1 (HIV-1) More
Total number of polymer chains	12
Total formula weight	312138.37
Authors	Gorman, J.,Kwong, P.D. (deposition date: 2024-04-16, release date: 2024-07-31)
Primary citation	Zhang, P.,Gorman, J.,Tsybovsky, Y.,Lu, M.,Liu, Q.,Gopan, V.,Singh, M.,Lin, Y.,Miao, H.,Seo, Y.,Kwon, A.,Olia, A.S.,Chuang, G.Y.,Geng, H.,Lai, Y.T.,Zhou, T.,Mascola, J.R.,Mothes, W.,Kwong, P.D.,Lusso, P. Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43:114518-114518, 2024 Cited by PubMed: 39028623 DOI: 10.1016/j.celrep.2024.114518 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation