9BC4

Transglutaminase 2 - Intermediate State

This is a non-PDB format compatible entry.

Summary for 9BC4

• Entry DOI: 10.2210/pdb9bc4/pdb
• Descriptor: Protein-glutamine gamma-glutamyltransferase 2, HB-225 (gluten peptidomimetic TG2 inhibitor), CALCIUM ION, ... (5 entities in total)
• Functional Keywords: transglutaminase 2, intermediate state, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 78265.79

Authors

Sewa, A.S.,Mathews, I.I.,Khosla, C. (deposition date: 2024-04-07, release date: 2024-07-03, Last modification date: 2024-07-17)

• Primary citation: Sewa, A.S.,Besser, H.A.,Mathews, I.I.,Khosla, C.; Structural and mechanistic analysis of Ca 2+ -dependent regulation of transglutaminase 2 activity using a Ca 2+ -bound intermediate state.; Proc.Natl.Acad.Sci.USA, 121:e2407066121-e2407066121, 2024; PubMed: 38959038; DOI: 10.1073/pnas.2407066121

Experimental method

X-RAY DIFFRACTION (1.84 Å)