9B74

Crystal structure of humanized 44H10 Fab Version 14

Summary for 9B74

• Entry DOI: 10.2210/pdb9b74/pdb
• Descriptor: h44H10-V14 Antibody, heavy chain, h44H10-V14 Antibody, light chain, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: antibody, humanized, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47742.07

Authors

Kassardjian, A.,Julien, J.P. (deposition date: 2024-03-27, release date: 2024-08-07)

• Primary citation: Kassardjian, A.,Ivanochko, D.,Barber, B.,Jetha, A.,Julien, J.P.; Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework.; Antibodies, 13:-, 2024; PubMed: 39051333; DOI: 10.3390/antib13030057

Experimental method

X-RAY DIFFRACTION (2.48 Å)