9B35

Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344

9B35 の概要

• エントリーDOI: 10.2210/pdb9b35/pdb
• EMDBエントリー: 44128
• 分子名称: Glutamate receptor ionotropic, kainate 2, GLUTAMIC ACID (2 entities in total)
• 機能のキーワード: kainate receptor, gluk2, positive allosteric modulator, bpam344, open, glutamate, lbd-tmd, ligand-binding domain, transmembrane domain, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 412494.86

構造登録者

Nadezhdin, K.D.,Gangwar, S.P.,Sobolevsky, A.I. (登録日: 2024-03-18, 公開日: 2024-05-22, 最終更新日: 2024-06-26)

• 主引用文献: Gangwar, S.P.,Yelshanskaya, M.V.,Nadezhdin, K.D.,Yen, L.Y.,Newton, T.P.,Aktolun, M.,Kurnikova, M.G.,Sobolevsky, A.I.; Kainate receptor channel opening and gating mechanism.; Nature, 630:762-768, 2024; PubMed: 38778115; DOI: 10.1038/s41586-024-07475-0

実験手法

ELECTRON MICROSCOPY (3.4 Å)