9AXO

Crystal Structure of Antibody HY11-7E1_Ch2 Fab in Complex with Fentanyl

Summary for 9AXO

• Entry DOI: 10.2210/pdb9axo/pdb
• Descriptor: HY11-7E1_Ch2 Fab Heavy Chain, HY11-7E1_Ch2 Fab Light Chain, GLYCEROL, ... (5 entities in total)
• Functional Keywords: opioids, mab, fentanyl, cross-reactive, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 50187.68

Authors

Rodarte, J.V.,Pancera, M. (deposition date: 2024-03-06, release date: 2024-10-02)

• Primary citation: Rodarte, J.V.,Pravetoni, M.; Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)