9ATN
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
Summary for 9ATN
Entry DOI | 10.2210/pdb9atn/pdb |
Descriptor | Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION (3 entities in total) |
Functional Keywords | mll4, transcription, protein binding, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 13263.89 |
Authors | |
Primary citation | Zhang, Y.,Xie, G.,Lee, J.E.,Zandian, M.,Sudarshan, D.,Estavoyer, B.,Benz, C.,Viita, T.,Asgaritarghi, G.,Lachance, C.,Messmer, C.,Simonetti, L.,Sinha, V.K.,Lambert, J.P.,Chen, Y.W.,Wang, S.P.,Ivarsson, Y.,Affar, E.B.,Cote, J.,Ge, K.,Kutateladze, T.G. ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers. Nat Commun, 15:4883-4883, 2024 Cited by PubMed: 38849395DOI: 10.1038/s41467-024-49391-x PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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