9ZWC

HSV1 gB dimer of prefusion-1 trimer and prefusion-2 trimer with "deliD" mutations

Summary for 9ZWC

• Entry DOI: 10.2210/pdb9zwc/pdb
• Related: 9ZQN 9ZUC 9ZUD 9ZUF 9ZUP 9ZVO 9ZVP 9ZVQ 9ZW2 9ZWH 9ZXO 9ZXP 9ZXQ 9ZXR 9ZXS 9ZXT 9ZXU 9ZXV 9ZXW
• EMDB information: 74805 74906
• Descriptor: HSV1 gB with "deliD" mutations, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: gb, glycoprotein b, herpesvirus, stabilization, stabilizing mutations, viral entry, vaccine, antigen, ebv, epstein-barr virus, prefusion, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein, herpes simplex, hsv-1, hsv-2
• Biological source: Human alphaherpesvirus 1 strain 17
• Total number of polymer chains: 6
• Total formula weight: 495588.35

Authors

McCallum, M.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2026-01-01, release date: 2026-11-04)

• Primary citation: McCallum, M.,Veesler, D.; Prefusion- stabilization of the Herpesvirus fusion protein enhances vaccine potency; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)