9Y9G

Cryo-EM structure of human CNNM4(K113A/R140A/R141A) tetramer with Magnesium and MgATP in outward-facing state

Summary for 9Y9G

Entry DOI	10.2210/pdb9y9g/pdb
Related	11GQ 9Y9D 9Y9F
EMDB information	72697
Descriptor	Metal transporter CNNM4, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywords	magnesium transporter, membrane protein, transmembrane domain, ion binding, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	378058.92
Authors	Bai, Z.,Zhou, E.,Lu, W.,Du, J. (deposition date: 2025-09-14, release date: 2026-07-29)
Primary citation	Bai, Z.,Zhou, E.,Lu, W.,Du, J. Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4 To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.89 Å)

Structure validation