9LTF

Crystal structure of mSTING-TTB

Summary for 9LTF

Entry DOI	10.2210/pdb9ltf/pdb
Descriptor	Stimulator of interferon genes protein, N-phenyl-7-(pyridin-4-ylmethoxy)furo[2,3-d]pyridazin-4-amine (3 entities in total)
Functional Keywords	inhibitor, complex, immune system
Biological source	Mus musculus (house mouse)
Total number of polymer chains	1
Total formula weight	21904.91
Authors	Zhang, C.G.,Hou, Y.F.,Liu, P.Y.,Fan, S.L. (deposition date: 2025-02-06, release date: 2026-02-11)
Primary citation	Zhang, C.G.,Hou, Y.F. Activation of STING by a VEGFR inhibitor telatinib with antitumor activity To Be Published,
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation