9HM1

Crystal structure of GSK3b in complex with N-(4-{5-[(2-aminoethyl)sulfamoyl]thiophen-2-yl}pyridin-2-yl)cyclopropanecarboxamide inhibitor

This is a non-PDB format compatible entry.

Summary for 9HM1

• Entry DOI: 10.2210/pdb9hm1/pdb
• Descriptor: Glycogen synthase kinase-3 beta, N-(4-{5-[(2-aminoethyl)sulfamoyl]thiophen-2-yl}pyridin-2-yl)cyclopropanecarboxamide (3 entities in total)
• Functional Keywords: kinase, kinase inhibitor, enzyme, alzheimer's disease, small molecule kinase inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 41951.11

Authors

Slugocka, E.A.,Grygier, P.,Wichur, T.,Czarna, A.,Wieckowska, A. (deposition date: 2024-12-06, release date: 2026-06-17)

• Primary citation: Slugocka, E.A.,Grygier, P.,Wichur, T.,Czarna, A.,Wieckowska, A.; Crystal structure of GSK3b in complex with N-(4-{5-[(2-aminoethyl)sulfamoyl]thiophen-2-yl}pyridin-2-yl)cyclopropanecarboxamide inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.45 Å)