9C61

Crystal structure of the human LRRK2 WDR domain in complex with CACHE1193-26

This is a non-PDB format compatible entry.

Summary for 9C61

• Entry DOI: 10.2210/pdb9c61/pdb
• Descriptor: Non-specific serine/threonine protein kinase, (4R)-4-[4-(5-fluoro-1H-indol-3-yl)piperidine-1-carbonyl]piperidin-2-one, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: wd-repeat, wdr, lrrk2, sgc, cytosolic protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 87965.60

Authors

Zeng, H.,Dong, A.,Kutera, M.,Ilyassov, O.,Seitova, A.,Loppnau, P.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L. (deposition date: 2024-06-07, release date: 2024-07-03)

• Primary citation: Zeng, H.,Dong, A.,Kutera, M.,Ilyassov, O.,Seitova, A.,Loppnau, P.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Crystal structure of the human LRRK2 WDR domain in complex with CACHE1193-26; To be published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)