9C61
Crystal structure of the human LRRK2 WDR domain in complex with CACHE1193-26
This is a non-PDB format compatible entry.
Summary for 9C61
Entry DOI | 10.2210/pdb9c61/pdb |
Descriptor | Non-specific serine/threonine protein kinase, (4R)-4-[4-(5-fluoro-1H-indol-3-yl)piperidine-1-carbonyl]piperidin-2-one, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | wd-repeat, wdr, lrrk2, sgc, cytosolic protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 87965.60 |
Authors | Zeng, H.,Dong, A.,Kutera, M.,Ilyassov, O.,Seitova, A.,Loppnau, P.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L. (deposition date: 2024-06-07, release date: 2024-07-03) |
Primary citation | Zeng, H.,Dong, A.,Kutera, M.,Ilyassov, O.,Seitova, A.,Loppnau, P.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L. Crystal structure of the human LRRK2 WDR domain in complex with CACHE1193-26 To be published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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