9BU1

Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with (6'-hydroxy-1'-(4-((1-propylazetidin-3-yl)methoxy)phenyl)-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone

This is a non-PDB format compatible entry.

Summary for 9BU1

• Entry DOI: 10.2210/pdb9bu1/pdb
• Descriptor: Estrogen receptor, [(1'R)-6'-hydroxy-1'-{4-[(1-propylazetidin-3-yl)methoxy]phenyl}-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl](phenyl)methanone (3 entities in total)
• Functional Keywords: estrogen receptor, estrogen, alpha helical bundle, breast cancer, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 61259.60

Authors

Young, K.S.,Fanning, S.W. (deposition date: 2024-05-16, release date: 2024-06-19)

• Primary citation: Fanning, S.W.; publication coming soon; To Be Published,

Experimental method