8ZBE

cryo-EM structure of the octreotide-bound SSTR5-Gi complex

Summary for 8ZBE

Entry DOI	10.2210/pdb8zbe/pdb
EMDB information	39901
Descriptor	Beta-2 adrenergic receptor,Somatostatin receptor type 5,lgbit (fusion protein), Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein subunit gamma, ... (6 entities in total)
Functional Keywords	sstr5, octreoitde, structural protein, membrane protein/immune system, membrane protein-immune system complex
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	185122.72
Authors	Li, Y.G.,Meng, X.Y.,Yang, X.R.,Ling, S.L.,Shi, P.,Tian, C.L.,Yang, F. (deposition date: 2024-04-26, release date: 2024-07-10)
Primary citation	Li, Y.G.,Meng, X.Y.,Yang, X.,Ling, S.L.,Shi, P.,Tian, C.L.,Yang, F. Structural insights into somatostatin receptor 5 bound with cyclic peptides. Acta Pharmacol.Sin., 2024 Cited by PubMed: 38926478 DOI: 10.1038/s41401-024-01314-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.24 Å)

Structure validation