8ZBE

cryo-EM structure of the octreotide-bound SSTR5-Gi complex

8ZBE の概要

• エントリーDOI: 10.2210/pdb8zbe/pdb
• EMDBエントリー: 39901
• 分子名称: Beta-2 adrenergic receptor,Somatostatin receptor type 5,lgbit (fusion protein), Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein subunit gamma, ... (6 entities in total)
• 機能のキーワード: sstr5, octreoitde, structural protein, membrane protein/immune system, membrane protein-immune system complex
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 185122.72

構造登録者

Li, Y.G.,Meng, X.Y.,Yang, X.R.,Ling, S.L.,Shi, P.,Tian, C.L.,Yang, F. (登録日: 2024-04-26, 公開日: 2024-07-10)

• 主引用文献: Li, Y.G.,Meng, X.Y.,Yang, X.,Ling, S.L.,Shi, P.,Tian, C.L.,Yang, F.; Structural insights into somatostatin receptor 5 bound with cyclic peptides.; Acta Pharmacol.Sin., 2024; PubMed: 38926478; DOI: 10.1038/s41401-024-01314-8

実験手法

ELECTRON MICROSCOPY (3.24 Å)