8Z8A

Cryo-EM structure of the Lactate-bound human HCAR1-Gi1 complex

Summary for 8Z8A

• Entry DOI: 10.2210/pdb8z8a/pdb
• EMDB information: 39843
• Descriptor: Hydroxycarboxylic acid receptor 1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• Functional Keywords: hydroxycarboxylic acid receptor, lactate, class a gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 152098.44

Authors

Gao, M.,Zang, S.,Zhu, Y.,Mao, C.,Zhang, Y.,Ma, X. (deposition date: 2024-04-21, release date: 2025-10-29)

• Primary citation: Gao, M.,Zang, S.,Zhu, Y.,Mao, C.,Zhang, Y.,Ma, X.; Cryo-EM structure of the Lactate-bound human HCAR1-Gi1 complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.82 Å)