8YPA

Human mitochondrial ClpP in complex with TR89

This is a non-PDB format compatible entry.

Summary for 8YPA

• Entry DOI: 10.2210/pdb8ypa/pdb
• Descriptor: ATP-dependent Clp protease proteolytic subunit, mitochondrial, (6~{R})-2-[[3,5-bis(fluoranyl)phenyl]methyl]-6-(hydroxymethyl)-5-[[4-(trifluoromethyl)phenyl]methyl]-7,8-dihydro-6~{H}-pyrazolo[1,5-a][1,4]diazepin-4-one (2 entities in total)
• Functional Keywords: mitochondria, caseinolytic protease p, activator, antitumor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 7
• Total formula weight: 173525.94

Authors

Li, Q.-N.,Sun, H.-Y.,Xiao, Y.-B. (deposition date: 2024-03-16, release date: 2025-03-19)

• Primary citation: Li, Q.-N.,Sun, H.-Y.,Xiao, Y.-B.; Human mitochondrial ClpP in complex with TR89; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.67 Å)