8YO8

Crystal structure of hFSP1 with both 6-OH-FAD and NAD (hFSP1-6-OH-FAD-NAD)

8YO8 の概要

• エントリーDOI: 10.2210/pdb8yo8/pdb
• 分子名称: Ferroptosis suppressor protein 1, SULFATE ION, 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• 機能のキーワード: flavoprotein, 6-oh-fad, redox, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41596.10

構造登録者

Lan, H.Y.,Gao, Y.,Hong, T.,Zhao, Z.Z.,Chang, Z.H.,Wang, Y.F.,Wang, F. (登録日: 2024-03-12, 公開日: 2025-01-08)

• 主引用文献: Lan, H.,Gao, Y.,Hong, T.,Chang, Z.,Zhao, Z.,Wang, Y.,Wang, F.; Structural insight into 6-OH-FAD-dependent activation of hFSP1 for ferroptosis suppression.; Cell Discov, 10:88-88, 2024; PubMed: 39160155; DOI: 10.1038/s41421-024-00723-7

実験手法

X-RAY DIFFRACTION (2 Å)