8YLS
Structure of SARS-CoV-2 Mpro in complex with its degrader
This is a non-PDB format compatible entry.
Summary for 8YLS
Entry DOI | 10.2210/pdb8yls/pdb |
Descriptor | 3C-like proteinase nsp5, (4-methoxyphenyl)methyl ~{N}-[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]carbamate (3 entities in total) |
Functional Keywords | severe acute respiratory syndrome coronavirus 2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 34259.04 |
Authors | Feng, Y.,Li, W.,Cheng, S.H.,Li, X.B. (deposition date: 2024-03-06, release date: 2024-09-04, Last modification date: 2024-09-18) |
Primary citation | Cheng, S.H.,Feng, Y.,Li, W.,Li, X.B. The Main Protease Degraders: Potent Broad-Spectrum Agents for Anti-Coronavirus Agents To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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