8YLA

Crystal structures of terpene synthases complexed with a substrate mimic

Summary for 8YLA

Entry DOI	10.2210/pdb8yla/pdb
Descriptor	Sesterfisherol synthase, MAGNESIUM ION, PYROPHOSPHATE, ... (5 entities in total)
Functional Keywords	sesterterpene synthase, terpene cyclase, sesterfisherol synthase, biosynthetic protein
Biological source	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Total number of polymer chains	2
Total formula weight	79303.39
Authors	Xu, M.,Ma, M. (deposition date: 2024-03-05, release date: 2024-04-24, Last modification date: 2024-06-12)
Primary citation	Xu, M.,Xu, H.,Lei, Z.,Xing, B.,Dickschat, J.S.,Yang, D.,Ma, M. Structural Insights Into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification. Angew.Chem.Int.Ed.Engl., 63:e202405140-e202405140, 2024 Cited by PubMed: 38584136 DOI: 10.1002/anie.202405140 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation