8YBJ

Cryo-EM structure of human nucleosome core particle composed of the Widom 601 DNA sequence

Summary for 8YBJ

• Entry DOI: 10.2210/pdb8ybj/pdb
• EMDB information: 39119
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total)
• Functional Keywords: chromatin, nucleosome, gene regulation, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 201635.02

Authors

Kimura, T.,Hirai, S.,Kujirai, T.,Ogasawara, M.,Takizawa, Y.,Kurumizaka, H. (deposition date: 2024-02-14, release date: 2024-07-24, Last modification date: 2024-09-11)

• Primary citation: Kimura, T.,Hirai, S.,Kujirai, T.,Fujita, R.,Ogasawara, M.,Ehara, H.,Sekine, S.I.,Takizawa, Y.,Kurumizaka, H.; Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.; Genes Cells, 29:769-781, 2024; PubMed: 38972377; DOI: 10.1111/gtc.13143

Experimental method

ELECTRON MICROSCOPY (2.38 Å)