8Y8J

Local structure of HCoV-HKU1C spike in complex with glycan

8Y8J の概要

• エントリーDOI: 10.2210/pdb8y8j/pdb
• EMDBエントリー: 39048
• 分子名称: Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hku1c, spike, tmprss2, viral protein
• 由来する生物種: Human coronavirus HKU1 (isolate N5)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 284443.62

構造登録者

Lu, Y.C.,Zhang, X.,Wang, H.F.,Sun, L.,Yang, H.T. (登録日: 2024-02-06, 公開日: 2024-07-17, 最終更新日: 2024-08-28)

• 主引用文献: Wang, H.,Liu, X.,Zhang, X.,Zhao, Z.,Lu, Y.,Pu, D.,Zhang, Z.,Chen, J.,Wang, Y.,Li, M.,Dong, X.,Duan, Y.,He, Y.,Mao, Q.,Guo, H.,Sun, H.,Zhou, Y.,Yang, Q.,Gao, Y.,Yang, X.,Cao, H.,Guddat, L.,Sun, L.,Rao, Z.,Yang, H.; TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.; Cell, 187:4261-, 2024; PubMed: 38964329; DOI: 10.1016/j.cell.2024.06.016

実験手法

ELECTRON MICROSCOPY (3.57 Å)