8Y8I

Structure of HCoV-HKU1C spike in the glycan-activated-3up conformation

Summary for 8Y8I

Entry DOI	10.2210/pdb8y8i/pdb
EMDB information	39047
Descriptor	Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	hku1c, spike, tmprss2, viral protein
Biological source	Human coronavirus HKU1 (isolate N5)
Total number of polymer chains	3
Total formula weight	422054.61
Authors	Lu, Y.C.,Zhang, X.,Wang, H.F.,Sun, L.,Yang, H.T. (deposition date: 2024-02-06, release date: 2024-07-17, Last modification date: 2024-08-28)
Primary citation	Wang, H.,Liu, X.,Zhang, X.,Zhao, Z.,Lu, Y.,Pu, D.,Zhang, Z.,Chen, J.,Wang, Y.,Li, M.,Dong, X.,Duan, Y.,He, Y.,Mao, Q.,Guo, H.,Sun, H.,Zhou, Y.,Yang, Q.,Gao, Y.,Yang, X.,Cao, H.,Guddat, L.,Sun, L.,Rao, Z.,Yang, H. TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187:4261-, 2024 Cited by PubMed: 38964329 DOI: 10.1016/j.cell.2024.06.016 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.58 Å)

Structure validation