8Y8H

Structure of HCoV-HKU1C spike in the glycan-activated-2up conformation

Summary for 8Y8H

Entry DOI	10.2210/pdb8y8h/pdb
EMDB information	39046
Descriptor	Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	hku1c, spike, tmprss2, viral protein
Biological source	Human coronavirus HKU1 (isolate N5) (HCoV-HKU1)
Total number of polymer chains	3
Total formula weight	423160.65
Authors	Lu, Y.C.,Zhang, X.,Wang, H.F.,Sun, L.,Yang, H.T. (deposition date: 2024-02-06, release date: 2024-07-17)
Primary citation	Wang, H.,Liu, X.,Zhang, X.,Zhao, Z.,Lu, Y.,Pu, D.,Zhang, Z.,Chen, J.,Wang, Y.,Li, M.,Dong, X.,Duan, Y.,He, Y.,Mao, Q.,Guo, H.,Sun, H.,Zhou, Y.,Yang, Q.,Gao, Y.,Yang, X.,Cao, H.,Guddat, L.,Sun, L.,Rao, Z.,Yang, H. TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 2024 Cited by PubMed: 38964329 DOI: 10.1016/j.cell.2024.06.016 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.65 Å)

Structure validation