8Y87
Structure of HCoV-HKU1C spike in the functionally anchored-1up conformation with 1TMPRSS2
Summary for 8Y87
Entry DOI | 10.2210/pdb8y87/pdb |
EMDB information | 39036 |
Descriptor | Spike glycoprotein, Transmembrane protease serine 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | hku1a, spike, tmprss2, viral protein |
Biological source | Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) More |
Total number of polymer chains | 4 |
Total formula weight | 469312.91 |
Authors | Lu, Y.C.,Zhang, X.,Wang, H.F.,Liu, X.C.,Sun, L.,Yang, H.T. (deposition date: 2024-02-06, release date: 2024-07-17, Last modification date: 2024-10-16) |
Primary citation | Wang, H.,Liu, X.,Zhang, X.,Zhao, Z.,Lu, Y.,Pu, D.,Zhang, Z.,Chen, J.,Wang, Y.,Li, M.,Dong, X.,Duan, Y.,He, Y.,Mao, Q.,Guo, H.,Sun, H.,Zhou, Y.,Yang, Q.,Gao, Y.,Yang, X.,Cao, H.,Guddat, L.,Sun, L.,Rao, Z.,Yang, H. TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187:4261-, 2024 Cited by PubMed: 38964329DOI: 10.1016/j.cell.2024.06.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.26 Å) |
Structure validation
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