8Y6K

Cryo-EM structure of full-length MICAL1 in the autoinhibited state

Summary for 8Y6K

• Entry DOI: 10.2210/pdb8y6k/pdb
• EMDB information: 38989
• Descriptor: [F-actin]-monooxygenase MICAL1, ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• Functional Keywords: mical1, monooxygenase, f-actin disassembly, autoinhibition, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 118931.10

Authors

Niu, F.,Wei, Z. (deposition date: 2024-02-02, release date: 2024-08-28, Last modification date: 2024-09-25)

• Primary citation: Lin, L.,Dong, J.,Xu, S.,Xiao, J.,Yu, C.,Niu, F.,Wei, Z.; Autoinhibition and relief mechanisms for MICAL monooxygenases in F-actin disassembly.; Nat Commun, 15:6824-6824, 2024; PubMed: 39122694; DOI: 10.1038/s41467-024-50940-7

Experimental method

ELECTRON MICROSCOPY (3.94 Å)